Belongs to workpackage health

P5: Ecobaby

Beneficiary 5. Ecobaby - Stichting Ecobaby, Amsterdam, The Netherlands

Beneficiary description - Stichting Ecobaby (Ecobaby) is a non-governmental organization promoting research and education in the field of environmental influences in pregnancy and outcome of the baby in later life. The foundation cooperates with the obstetric- and children’s department of the EKZ-Academic Medical Center of the University of Amsterdam and the big regional hospital the “Westfriesgasthuis” in Hoorn, The Netherlands. Ecobaby is part of an international network on neonatology: The International Perinatal Collegium.
Key personnel - Janna Koppe, chairman Ecobaby, former professor in Neonatology at the University of Amsterdam. Since 1965 she is involved in studies on effects of anti-epileptic drugs, antenatal steroids, surfactant-replacement (after birth), maternal under-nutrition, and dioxins in pregnancy and outcome of the baby.
Key role – Beneficiary 5 will contribute to the risk assessment work package WP 3 to contribute strategies for Prevention, Cure or Mitigation of damage due to endocrine disruption (obesity and diabetes) caused by environmental pollutants in the perinatal period (conception, pregnancy and infancy). Existing data of the ongoing long-term study in mother-baby pairs (the Amsterdam-Zaandam cohort) to health effects of perinatal dioxin and brominated flame retardant exposure will be made available.
Key References
• Leijs MM, ten Tusscher GW, Olie K, van Aalderen WMC, Vulsma T, Westra M, Oosting J, & Koppe JG. 2008. Perinatal dioxin exposure in The Netherlands – a long-term follow-up. Int. J. Environment and Health, in press.
• Leijs MM, Koppe JG, Olie K, de Voogt P, Vulsma T, van Aalderen WMC, Westra M, & ten Tusscher GW. 2008, Delayed initiation of breast development in girls with higher prenatal dioxin exposure: a longitudinal cohort study. Chemosphere 73, 999–1004
• Smolders-de Haas, Neuvel J., Schmand B., Treffers, P. E., Koppe J.G., & Hoeks J. 1990, Physical Development and Medical History of Children Who Were Treated Antenatally With Corticosteroids to Prevent Respiratory Distres Syndrome: A 10-12-Year Follow-up. Pediatrics, vol. 86, pp. 65-70.
• tenTusscher G.W., Weerdt, Roos C.M., Griffioen R.W., De Jongh F.H., Westra M., Slikke J.W.van der, Oosting J., Olie K., & Koppe J.G. 2001, Decreased lung function associated with perinatal exposure to Dutch background levels of dioxins. Acta Paediatr., vol. 90, pp. 1292-1298.
• Dessens A.B., Cohen-Kettenis P.T., Mellenbergh G., v.d.Poll N.E., Koppe J.G., & Boer K. 1999, Prenatal exposure to Anticonvulsants and Psychosexual Development. Archives of sexual behaviour, vol. 28 nr 1, pp. 31-45.

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